Bhawan J, Chang W H
Dermatologica. 1979;159(3):221-30. doi: 10.1159/000250598.
Becker's melanosis is an uncommon condition characterized by hypertrichosis, hyperpigmentation of the epidermis, dermal melanophages and absence of nevus cells. Ultrastructural examination of such a melanotic lesion from a young white man revealed giant melanosomes. In addition, normal-sized melanosomes were found singly in the keratinocytes of the involved skin. Dermal venules were surrounded by multiple layers of basement membrane.
贝克尔黑变病是一种罕见病症,其特征为多毛症、表皮色素沉着、真皮噬黑素细胞以及无痣细胞。对一名年轻白人男性的此类黑素沉着性病变进行超微结构检查发现了巨大黑素小体。此外,在受累皮肤的角质形成细胞中单独发现了正常大小的黑素小体。真皮小静脉被多层基底膜包围。