Chapel T A, Tavafoghi V, Mehregan A H, Gagliardi C
Cutis. 1981 Apr;27(4):405-6, 410, 415.
Herein we have reported the histologic findings in two cases of Becker's melanosis. In one patient the lesion showed hyperplasia or hair muscles and in the other patient the lesion was associated with an underlying neurofibroma. The proliferative changes seen in the epidermis and dermis in Becker's melanosis can best be explained by the concept of an organoid hamartoma with involvement of the epidermis, pilar structures, and some other dermal components. The localization of the plexiform neurofibroma within the Becker's nervus is a unique observation. It may fall within the spectrum of an organoid hamartoma or it may only represent a chance occurrence.
在此,我们报告了两例贝克痣的组织学发现。在一例患者中,病变显示毛发肌肉增生,而在另一例患者中,病变与潜在的神经纤维瘤相关。贝克痣中表皮和真皮出现的增殖性变化,最好用类器官错构瘤的概念来解释,即表皮、毛囊结构和其他一些真皮成分受累。丛状神经纤维瘤在贝克痣神经内的定位是一个独特的观察结果。它可能属于类器官错构瘤的范畴,也可能只是一种偶然现象。