Caporicci D, Mori A, Maurizi G
G Ital Cardiol. 1979;9(5):535-9.
The authors exhibit the results obtained in 25 patients sumministring bunaftine in 3 mg/Kg in 1-2 min in rapid bolus i.v. By means a continuous ECG registration they could state that the antiarrhythmic effect is simultaneous with the distribution of the drug, obtaining the restoration of the sinus rhythm in about 90% of the patients. The Authors remark the lack of meaningful collateral effect by means a pre-treatment with diazepam-cortisone, according to their method.
作者展示了25例患者的结果,这些患者以3毫克/千克的剂量在1至2分钟内通过快速静脉推注给予布那非汀。通过连续心电图记录,他们指出抗心律失常作用与药物分布同时发生,约90%的患者恢复了窦性心律。作者指出,根据他们的方法,通过地西泮 - 可的松预处理,没有明显的副作用。