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半乳糖代谢中的性别差异:小鼠肾脏中的半乳糖基神经酰胺半乳糖苷酶及其他半乳糖苷酶

Sexual differences in galactose metabolism: galactosyl ceramide galactosidase and other galactosidases in mouse kidney.

作者信息

Lin Y N, Radin N S

出版信息

Biochem J. 1973 Dec;136(4):1125-7. doi: 10.1042/bj1361125.

Abstract

Male and female mice were compared at two ages, 15 and 50 days, with respect to the activities of three galactosidases in kidney. No sex difference in enzyme activity was seen in the young mice, but appreciable differences were found in the older animals. The male kidneys had about one-third higher specific activities of cerebroside beta-galactosidase and nitrophenyl beta-galactosidase, but there was no difference with nitrophenyl alpha-galactosidase. A listing and discussion of other galactose-metabolizing enzymes influenced by sex differences is presented.

摘要

对15日龄和50日龄的雄性和雌性小鼠肾脏中的三种半乳糖苷酶活性进行了比较。在幼龄小鼠中未观察到酶活性的性别差异,但在老龄动物中发现了明显差异。雄性小鼠肾脏中脑苷脂β - 半乳糖苷酶和硝基苯基β - 半乳糖苷酶的比活性高出约三分之一,但硝基苯基α - 半乳糖苷酶没有差异。本文列出并讨论了受性别差异影响的其他半乳糖代谢酶。

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本文引用的文献

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Biochim Biophys Acta. 1958 Oct;30(1):206-7. doi: 10.1016/0006-3002(58)90271-3.
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