Haemmerli G, Felix H, Sträuli P
Isr J Med Sci. 1979 Aug;15(8):653-9.
Dynamic morphology, which describes the shape and surface architecture of fixed cells in terms related to their behavior in the living state, is based on the concurrent use of two methods: scanning electron microscopy and microcinematography. This combination has both advantages and disadvantages. In this study on leukemic cells, we were able to draw the following conclusions about the usefulness of dynamic morphology. It confirms that white blood cells do not flatten on a glass substrate; they stay spherical and are either round or polarized. Round cells of similar size, whatever their origin, cannot be classified by dynamic morphology. Polarized cells can be classified as blasts, promyelocytes, myelocytes, granulocytes and lymphocytes, although polarized blast cells of different origins cannot be differentiated. Dynamic morphology cannot classify the same cell type as benign or malignant.
动态形态学是根据固定细胞在活态下的行为相关术语来描述其形状和表面结构的，它基于两种方法的同时使用：扫描电子显微镜和显微电影摄影术。这种结合既有优点也有缺点。在这项关于白血病细胞的研究中，我们能够就动态形态学的有用性得出以下结论。它证实白细胞不会在玻璃基质上变平；它们保持球形，要么是圆形要么是极化的。大小相似的圆形细胞，无论其来源如何，都无法通过动态形态学进行分类。极化细胞可分为原始细胞、早幼粒细胞、中幼粒细胞、粒细胞和淋巴细胞，尽管不同来源的极化原始细胞无法区分。动态形态学无法将同一细胞类型分类为良性或恶性。
