Haemmerli G, Felix H
Scan Electron Microsc. 1982(Pt 2):731-9.
By the concurrent use of scanning electron microscopy (SEM) and time lapse cinematography the interdependence of cellular shape and motility was visualized for leukemia cells and for normal and malignant epithelial cells. During the different modes of motility (stationary without net translocation of the whole cell, and locomotion), the cells display a distinct configuration. This allows the interpretation of static images in terms usually reserved for the description of activities of living cells. The ability of cells to change shape is of special importance when they migrate in the body. Irrespective of nature and origin, these cells must continuously adapt their configuration to the structural elements which they encounter in their pathways. The existence of such an adaptability could be shown by time lapse films for leukemia cells and for cells of the V2 rabbit carcinoma moving in mesenteries of rat and rabbit, respectively.
通过同时使用扫描电子显微镜（SEM）和延时摄影技术，观察到白血病细胞以及正常和恶性上皮细胞的细胞形状与运动之间的相互依存关系。在不同的运动模式下（细胞整体无净位移的静止状态和移动状态），细胞呈现出独特的形态。这使得通常用于描述活细胞活动的术语能够用于解释静态图像。细胞改变形状的能力在其在体内迁移时尤为重要。无论细胞的性质和来源如何，这些细胞都必须不断调整其形态以适应其在迁移路径中遇到的结构元件。通过延时电影可以证明白血病细胞以及分别在大鼠和兔子肠系膜中移动的V2兔癌细胞存在这种适应性。
