痘苗病毒感染后早期，L细胞在密度梯度中的沉降变化。
Sedimentation changes of L cells in a density gradient early after infection with vaccinia virus.
作者信息
Ball F R, Medzon E L
出版信息
J Virol. 1973 Sep;12(3):588-93. doi: 10.1128/JVI.12.3.588-593.1973.
Abstract
By 2 h postinfection, LM cells infected with vaccinia virus show a shift in their distribution when separated on a Ficoll density gradient. This shift is dependent on both time and the multiplicity of infection and is due, at least in part, to an increase in cell size. Those cells which do shift in position in the gradient represent infected members of the population. Physical changes induced in virus-infected cells can be utilized for studying early events in virus replication.
摘要
感染后2小时，感染痘苗病毒的LM细胞在Ficoll密度梯度上分离时，其分布会发生变化。这种变化取决于时间和感染复数，并且至少部分是由于细胞大小增加所致。那些在梯度中位置发生变化的细胞代表群体中的感染细胞。病毒感染细胞中诱导的物理变化可用于研究病毒复制的早期事件。
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