Barbour G L, Joe C, Patterson R M
J Lab Clin Med. 1979 Oct;94(4):526-31.
Twelve chronic peritoneal dialysis patients were studied on 20 occasions to measure peritoneal clearances of creatinine, urea, uric acid, and potassium. Two clearance techniques were employed, the classical type using timed collections and a midpoint blood specimen and an experimental type using calculated dialysate flow and predialysis peritoneal fluid solute concentrations. Comparison of the two techniques demonstrated a close correlation between simultaneously measured clearances and also for repeat measurements in the same patient. The new technique is simple and reproducible, does not require blood sampling, and can be performed in the home by patients treated by self-dialysis using automated peritoneal dialysis equipment. The new technique will allow more frequent monitoring of peritoneal permeance in self-dialysis patients, and necessary adjustments in treatment time can be prescribed without requiring hospitalization.
对12名慢性腹膜透析患者进行了20次研究，以测量肌酐、尿素、尿酸和钾的腹膜清除率。采用了两种清除率测量技术，一种是传统类型，即定时收集并采集血样中点标本；另一种是实验类型，即利用计算得出的透析液流量和透析前腹膜液溶质浓度。两种技术的比较表明，同时测量的清除率之间以及同一患者的重复测量结果之间存在密切相关性。新技术简单且可重复，无需采血，使用自动腹膜透析设备进行自我透析治疗的患者可在家中操作。新技术将使自我透析患者能够更频繁地监测腹膜通透性，并且无需住院即可规定必要的治疗时间调整。
