Oestrogenic effects of catechol oestrogens on secretion of prolactin by the pituitary gland and synthesis of DNA by the mammary gland in ovariectomized rats.
作者信息
Yanai R, Nagasawa H
出版信息
J Endocrinol. 1979 Jul;82(1):131-3. doi: 10.1677/joe.0.0820131.
PMID:479728
Abstract
The effects of 2-hydroxyoestradiol-17 beta and 2-hydroxyoestriol (2OH-OE3) on levels of serum prolactin, DNA synthesis by the mammary gland and the weight of the uterus were examined in ovariectomized Sprague-Dawley rats. 2-Hydroxyoestradiol-17 beta had a potent oestrogenic activity in stimulating the secretion of prolactin by the pituitary gland, the synthesis of DNA by the mammary gland and in increasing the weight of the uterus. On the other hand, 2OH-OE3 increased the weight of the uterus only.
摘要
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