• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

丁酰苯和二苯基丁基哌啶类化合物与吩噻嗪衍生物的薄层色谱鉴别

TLC differentiation of butyrophenone and diphenylbutylpiperidine compounds from phenothiazine derivatives.

作者信息

Pluym A

出版信息

J Pharm Sci. 1979 Aug;68(8):1050-2. doi: 10.1002/jps.2600680834.

DOI:10.1002/jps.2600680834
PMID:480160
Abstract

A procedure is described for TLC detection and differentiation of the butyrophenone-diphenylbutylpiperidine group and phenothiazine derivatives at the microgram level. A two-dimensional TLC method to separate butyrophenone and diphenylbutylpiperidine compounds is reported. A variety of possible detection reagents were examined. The solvent systems and spray reagents described should be useful for the identification of these drugs in various dosage forms.

摘要

本文描述了一种用于在微克水平检测和区分丁酰苯-二苯基丁基哌啶类和吩噻嗪衍生物的薄层色谱法。报道了一种二维薄层色谱法用于分离丁酰苯和二苯基丁基哌啶化合物。对多种可能的检测试剂进行了考察。所描述的溶剂系统和喷雾试剂应有助于鉴定各种剂型中的这些药物。

相似文献

1
TLC differentiation of butyrophenone and diphenylbutylpiperidine compounds from phenothiazine derivatives.丁酰苯和二苯基丁基哌啶类化合物与吩噻嗪衍生物的薄层色谱鉴别
J Pharm Sci. 1979 Aug;68(8):1050-2. doi: 10.1002/jps.2600680834.
2
Determination of drugs containing fluorine with ion-selective electrode. Part 2: Butyrophenones and bis(4-fluorophenyl)butylpiperidines.用离子选择电极测定含氟药物。第2部分：丁酰苯类和双（4-氟苯基）丁基哌啶类
Pharmazie. 1989 Jan;44(1):65.
3
[Neuroleptics with prolonged action].[长效抗精神病药物]
Neurol Neurocir Psiquiatr. 1976;17(1):35-45.
4
[Possibilities for detecting low dosage and highly active drugs in the butyrophenone and diphenylbutylpiperidine series].[检测丁酰苯类和二苯基丁基哌啶类低剂量高活性药物的可能性]
Beitr Gerichtl Med. 1984;42:81-4.
5
Densitometric determination of impurities in pharmaceuticals. Part VI. Determination of 4,4-bis[4-(p-chlorophenyl)- 4-hydroxypiperidino]butyrophenone in haloperidol.药物中杂质的密度测定法。第六部分。氟哌啶醇中4,4 - 双[4 -（对氯苯基）- 4 - 羟基哌啶基]丁酰苯的测定。
Acta Pol Pharm. 2000 Jan-Feb;57(1):23-6.
6
Diazotized sulfanilic acid as a novel reagent for the detection of phenothiazine, phenothiazine-like drugs and their decomposition products in pharmaceuticals.
Pharmazie. 1984 Oct;39(10):718.
7
The use of electron-acceptor reagents for the non-destructive detection of some phenothiazine derivatives on thin layers.用于在薄层上无损检测某些吩噻嗪衍生物的电子受体试剂的应用。
J Chromatogr. 1973 Jan 3;75(1):156-9. doi: 10.1016/s0021-9673(01)83430-0.
8
Thin-layer chromatography of phenothiazine derivatives and analogues.吩噻嗪衍生物及类似物的薄层色谱法。
J Chromatogr. 1973 Jan 3;75(1):79-86. doi: 10.1016/s0021-9673(01)83414-2.
9
[Analytical study of drugs from the group of phenothiazine derivatives. VII. Identification of diphenylamine in phenothiazine by thin layer chromatography].[吩噻嗪衍生物类药物的分析研究。VII. 用薄层色谱法鉴定吩噻嗪中的二苯胺]
Cesk Farm. 1969 Nov;18(9):483-5.
10
Antischizophrenic drugs of the diphenylbutylpiperidine type act as calcium channel antagonists.二苯基丁基哌啶类抗精神分裂症药物作为钙通道拮抗剂发挥作用。
Proc Natl Acad Sci U S A. 1983 Aug;80(16):5122-5. doi: 10.1073/pnas.80.16.5122.

引用本文的文献

1
Changes in circulating androgens during short term carbamazepine therapy.短期卡马西平治疗期间循环雄激素的变化。
Br J Clin Pharmacol. 1984 Mar;17(3):347-51. doi: 10.1111/j.1365-2125.1984.tb02352.x.