[Changes in lactate dehydrogenase, glutamate-cxaloacetate transaminase and glutamate-pyruvate transaminase in several muscular atrophies. I. Changes following tenotomy].

The activites of lactic dehydrogenase (LDH), glutamicoxalactic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) are investigated within variable periods following tenotomy of m. gastrocnemius in the rat. A gradual fall of total activities is established, mostly significant for LDH, and least - for GPT. The specific activities undergo similar alterations. Experiments with dialysates show that the changes found are due to a reduced enzyme molecules' synthesis, and not to altered ratios between enzyme activators and inhibitors.