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菲律宾日本血吸虫感染的纵向研究。莱特省达加米地区学童的发病率和患病率。

Longitudinal study on Schistosoma japonicum infections in the Philippines. Incidence and prevalence among school children in Dagami Area, Leyte.

作者信息

Blas B L, Noseñas J S, Tanaka H, Matsudo O, Onodera N, Matsuda H, Hashiguchi J, Santos A T

出版信息

Jpn J Exp Med. 1979 Apr;49(2):107-15.

PMID:480676
Abstract

The annual incidence of Schistosoma japonicum infection was calculated from the record of the yearly examination among school children of Dagami Area, Leyte, Philippines. Data were processed mainly by the computer. Children were examined for eggs by the merthiolate formalin concentration technique and by the circumoval precipitin test (COPT) once a year in 3 consecutive school years (SY), SY 1974/75, 1975/76 and 1976/77. About 600 to 700 children were examined yearly and the ratios of cases rechecked after 1 year were about 30%. A method to calculate the overall incidence in children who were examined at different intervals, was newly established. The incidence appeared to rise rapidly in the survey period, being 25.59% and 41.30% by fecal examination and 10.74% and 21.27% by COPT in SY 1975/76 and 1976/77, respectively. From the combined results of fecal examination and COPT, the reliable values of incidence, however, were shown to be stable during 2 years such as 22.06% and 24.21%, respectively. The incidence estimated by the age prevalence data was 20.25% in SY 1976/77 by the combined results and was found to be lower than the directly calculated value.

摘要

日本血吸虫感染的年发病率是根据菲律宾莱特省达加米地区学童年度检查记录计算得出的。数据主要通过计算机处理。在连续3个学年(1974/75学年、1975/76学年和1976/77学年)中,每年使用硫柳汞福尔马林浓缩技术和环卵沉淀试验(COPT)对儿童进行一次虫卵检查。每年检查约600至700名儿童,1年后复查的病例比例约为30%。新建立了一种计算不同间隔检查儿童总体发病率的方法。在调查期间,发病率似乎迅速上升,在1975/76学年和1976/77学年,粪便检查的发病率分别为25.59%和41.30%,COPT检查的发病率分别为10.74%和21.27%。然而,从粪便检查和COPT的综合结果来看,发病率的可靠值在2年内保持稳定,分别为22.06%和24.21%。根据年龄患病率数据估计,1976/77学年综合结果的发病率为20.25%,低于直接计算值。

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