发作性睡病
Narcolepsy.
作者信息
Murray T J, Foley A
出版信息
Can Med Assoc J. 1974 Jan 5;110(1):63-6.
NARCOLEPSY IS A DISORDER OF SLEEP CONTROL CHARACTERIZED BY A TETRAD OF SYMPTOMS
sleep attacks, cataplexy, sleep paralysis and hypnagogic hallucinations. A diagnosis is made from a careful history. The incidence is estimated as high as 0.3% of the population. Unfortunately patients go for many years before the diagnosis is made and often have experienced disruption of their employment, social and family life, and may have experienced a number of car accidents because of falling asleep at the wheel. An unknown number of narcoleptics kill themselves on the highways before the diagnosis is ever made. Sleep attacks can usually be controlled by methylphenidate, and if the other symptoms persist they can often be effectively managed by imipramine.
发作性睡病是一种睡眠控制障碍，其特征为四联症：睡眠发作、猝倒、睡眠麻痹和入睡前幻觉。通过详细的病史来做出诊断。据估计，其发病率高达人群的0.3%。不幸的是，患者在确诊前要经历许多年，常常经历工作、社交和家庭生活的中断，并且可能因驾车时入睡而遭遇多次车祸。在确诊前，有未知数量的发作性睡病患者在高速公路上自杀。睡眠发作通常可用哌甲酯控制，如果其他症状持续存在，常可用丙咪嗪有效控制。
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