淋巴细胞依赖性抗体与肾移植排斥反应。
Lymphocyte-dependent antibody and renal graft rejection.
作者信息
Stiller C R, Sinclair N R, Abrahams S, Ulan R A, Fung M, Wallace A C
出版信息
Lancet. 1975 Apr 26;1(7913):953-4. doi: 10.1016/s0140-6736(75)92010-3.
A patient with preformed cytotoxic lymphocyte-dependent antibody (L.D.A.) against the specific renal transplant donor rapidly rejected the grafted kidney. The characteristics of rejection were not those of hyperacute rejection due to cytotoxic complement-dependent antibody or of acute rejection is attributed to the cytotoxic activity of L.D.A. The avoidance of transplants based on positive crossmatches by the L.D.A. test or at least the carrying out of the L.D.A. crossmatch is advised.
一名对特定肾移植供体预先形成细胞毒性淋巴细胞依赖性抗体（L.D.A.）的患者迅速排斥了移植的肾脏。排斥反应的特征既不是由细胞毒性补体依赖性抗体引起的超急性排斥反应的特征，也不是由L.D.A.的细胞毒性活性导致的急性排斥反应的特征。建议避免基于L.D.A.试验阳性交叉配型的移植，或者至少进行L.D.A.交叉配型。
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