Longpré B, Madarnas P, Cousineau L, Rochon M, Filion S
Can Med Assoc J. 1974 Mar 16;110(6):645-8.
Scleronodular type of Hodgkin's disease: experience at the Centre hospitalier universitaire de Sherbrooke The nodular sclerosis type of Hodgkin's disease appears to be a distinct clinical entity. However, the incidence, the initial localization of the tumour and the survival of the patients are variable. The present study was carried out on a group of 17 patients, all French Canadians living in the province of Quebec, from a total of 31 with Hodgkin's disease, an incidence of 55%. There were more males (10) than females (7). The mean age of the group was 37 years, but that of the females was lower than that of the males. The mediastinum was involved at the onset in 47% of the patients. The initial staging (according to the classification of Rye) in 76% of the patients was I or II. Four patients showed disease below the diaphragm. The lungs were infiltrated three times, the spleen six times, and the liver five times. The duration of survival of the 17 patients was twice that of the patients with the three other types of the disease.
舍布鲁克大学中心医院的经验 霍奇金病的结节硬化型似乎是一种独特的临床实体。然而,其发病率、肿瘤的初始定位以及患者的生存率各不相同。本研究针对一组17名患者开展,这些患者均为居住在魁北克省的法裔加拿大人,在总共31例霍奇金病患者中占55%。男性(10例)多于女性(7例)。该组患者的平均年龄为37岁,但女性的平均年龄低于男性。47%的患者起病时纵隔受累。76%的患者初始分期(根据赖伊分类法)为I期或II期。4例患者显示横膈以下有病变。肺部浸润3次,脾脏6次,肝脏5次。这17例患者的生存时间是其他三种类型疾病患者的两倍。