Elliott E, Moncrieff M W, George W H
Arch Dis Child. 1974 Jan;49(1):60-2. doi: 10.1136/adc.49.1.60.
Eighty-eight babies whose birthweights were between 1500 g and 2500 g, and whose serum bilirubin reached 10 mg/100 ml, were entered into a controlled trial of phototherapy. Alternate babies were treated with 4000 to 5000 lux, and control cases were not treated unless the bilirubin exceeded 15 mg/100 ml. No baby in the treated group developed a serum bilirubin greater than 15 mg/100 ml, compared with 44% of untreated cases, a highly significant difference. No side effects occurred apart from overheating in a few babies. We conclude that phototherapy is a safe and effective way of treating hyperbilirubinaemia in low birthweight infants, and suggest it should be started when the bilirubin reaches 12 mg/100 ml, except for babies under 1500 g birthweight when it should be started at 10 mg/100 ml.
88名出生体重在1500克至2500克之间且血清胆红素达到10毫克/100毫升的婴儿进入了一项光疗对照试验。每隔一个婴儿接受4000至5000勒克斯的光照治疗，除非胆红素超过15毫克/100毫升，否则对照病例不进行治疗。治疗组中没有婴儿的血清胆红素超过15毫克/100毫升，而未治疗组这一比例为44%，差异极具显著性。除了少数婴儿出现过热外，未发生其他副作用。我们得出结论，光疗是治疗低体重婴儿高胆红素血症的一种安全有效的方法，并建议当胆红素达到12毫克/100毫升时开始光疗，出生体重低于1500克的婴儿则应在胆红素达到10毫克/100毫升时开始光疗。
