Court J M, Dunlop M E, Boulton T J
Arch Dis Child. 1974 Jan;49(1):63-5. doi: 10.1136/adc.49.1.63.
The effect of oral ephedrine administration on a child with ketotic hypoglycaemia who had not responded to dietary measures alone was studied. After ephedrine administration, the hypoglycaemia developing after ketogenic stress was less profound and was substantially delayed. The impaired glycaemic response to glucagon during hypoglycaemia, characteristic of ketotic hypoglycaemia, was not altered. These observations are compatible with the proposition that ketotic hypoglycaemia is associated with impaired gluconeogenesis and they suggest that ephedrine may be a useful adjunct to therapy in this condition.
研究了口服麻黄碱对一名仅通过饮食措施治疗无效的酮症低血糖患儿的影响。服用麻黄碱后，生酮应激后出现的低血糖症状减轻且明显延迟。低血糖期间对胰高血糖素的血糖反应受损，这是酮症低血糖的特征，并未改变。这些观察结果与酮症低血糖与糖异生受损有关的观点一致，并且表明麻黄碱可能是这种情况下治疗的有用辅助药物。
