Marinone G, Maiolini E, Buttolo Q, Mauro P L, Colle R
Minerva Med. 1975 Apr 25;66(31):1466-71.
Treatment of advanced Hodgkin's disease by associating vincristine, adriblastine, prednisone and procarbazine is compared with other widely employed protocols. Most subjects in the series had already received one or more drugs and had relapsed. In spite of this, 60% were still in complete remission one year after the administration of 6 courses of the new association. An account is given of maintenance therapy in Hodgkin's disease once remission is obtained, and the problems thus raised are illustrated.
将长春新碱、阿霉素、强的松和甲基苄肼联合用于晚期霍奇金病的治疗,并与其他广泛应用的方案进行比较。该系列中的大多数受试者已经接受过一种或多种药物治疗且病情复发。尽管如此,在给予6个疗程的新联合方案治疗一年后,60%的患者仍处于完全缓解状态。文中介绍了霍奇金病缓解后维持治疗的情况,并阐述了由此引发的问题。