Mant T G
Postgrad Med J. 1979 Jun;55(644):421-2. doi: 10.1136/pgmj.55.644.421.
Malabsorption of prednisolone administered as enteric coated tablets was suspected following therapeutic failure in an asthmatic. This was investigated by cortisol estimation and a Synacthen test and substantiated by the demonstration of abnormally low absorption of prednisolone from these tablets which nevertheless were normally absorbed by a volunteer. The absorption of prednisolone from conventional tablets in this patient was normal.
一名哮喘患者治疗失败后，怀疑其对肠溶衣片形式给药的泼尼松龙存在吸收不良。通过皮质醇测定和促肾上腺皮质激素试验对此进行了调查，并通过证明这些片剂中泼尼松龙的吸收异常低得到证实，不过一名志愿者对这些片剂的吸收正常。该患者对常规片剂中泼尼松龙的吸收是正常的。
