一例泼尼松龙吸收不良病例的调查。
Investigation of a case of prednisolone malabsorption.
作者信息
Mant T G
出版信息
Postgrad Med J. 1979 Jun;55(644):421-2. doi: 10.1136/pgmj.55.644.421.
Abstract
Malabsorption of prednisolone administered as enteric coated tablets was suspected following therapeutic failure in an asthmatic. This was investigated by cortisol estimation and a Synacthen test and substantiated by the demonstration of abnormally low absorption of prednisolone from these tablets which nevertheless were normally absorbed by a volunteer. The absorption of prednisolone from conventional tablets in this patient was normal.
摘要
一名哮喘患者治疗失败后，怀疑其对肠溶衣片形式给药的泼尼松龙存在吸收不良。通过皮质醇测定和促肾上腺皮质激素试验对此进行了调查，并通过证明这些片剂中泼尼松龙的吸收异常低得到证实，不过一名志愿者对这些片剂的吸收正常。该患者对常规片剂中泼尼松龙的吸收是正常的。
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本文引用的文献
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Response of infants to a third dose of poliomyelitis vaccine given 10 to 12 months after primary immunization.婴儿在初次免疫后10至12个月接种第三剂脊髓灰质炎疫苗的反应。
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Drug absorption in gastrointestinal disease with particular reference to malabsorption syndromes.胃肠道疾病中的药物吸收，特别涉及吸收不良综合征。
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