泼尼松治疗对静脉用氢化可的松半衰期的影响。
The effect of prednisone treatment on the half-life of intravenous hydrocortisone.
机构信息
Asthma Research Concil Clinical Pharmacology Unit, Departmet of Medicine, Cardiothoracic Institute, Fulham Road, London.
出版信息
Br J Clin Pharmacol. 1974 Jun;1(3):237-40. doi: 10.1111/j.1365-2125.1974.tb00243.x.
Abstract
1 The half-life of hydrocortisone (cortisol) has been measured in six patients before and after a three-week course of prednisone given for asthma. 2 There was considerable variation in peak plasma level of cortisol both within and between patients, but on both occasions the plasma half-lives were the same. 3 It was concluded that short courses of prednisone have no effect on the handling of hydrocortisone.
摘要
在 6 名因哮喘接受 3 周泼尼松治疗的患者中，测量了氢化可的松（皮质醇）的半衰期。
皮质醇的血浆峰浓度在患者内和患者间均有很大差异，但两次的血浆半衰期均相同。
结论是，短期泼尼松治疗对氢化可的松的处理没有影响。
相似文献
1
The effect of prednisone treatment on the half-life of intravenous hydrocortisone.
Br J Clin Pharmacol. 1974 Jun;1(3):237-40. doi: 10.1111/j.1365-2125.1974.tb00243.x.
2
Adrenal response to serial cosyntropin stimulation after repeated high-dose prednisone administration in patients with lymphoma.
Cancer Treat Rep. 1981 Jul-Aug;65(7-8):563-6.
3
Variation in absorption and half-life of hydrocortisone influence plasma cortisol concentrations.
Clin Endocrinol (Oxf). 2015 Apr;82(4):557-61. doi: 10.1111/cen.12653. Epub 2014 Dec 19.
4
Comparison of inhaled beclomethasone dipropionate 1000 micrograms twice daily and oral prednisone 10 mg once daily in asthmatic patients.
Thorax. 1994 Jan;49(1):37-40. doi: 10.1136/thx.49.1.37.
5
Effects of short-term nocturnal cortisol replacement on cognitive function and quality of life in patients with primary or secondary adrenal insufficiency: a pilot study.
Appl Psychophysiol Biofeedback. 2009 Jun;34(2):113-9. doi: 10.1007/s10484-009-9082-5. Epub 2009 Apr 23.
6
Sources of sampling variation in saliva cortisol in dogs.
Res Vet Sci. 2003 Oct;75(2):157-61. doi: 10.1016/s0034-5288(03)00080-8.
7
Hypothalamic-pituitary-adrenal function one week after a short burst of steroid therapy.
J Clin Endocrinol Metab. 1993 May;76(5):1188-91. doi: 10.1210/jcem.76.5.8388401.
8
Plasma, salivary and urinary cortisol levels following physiological and stress doses of hydrocortisone in normal volunteers.
BMC Endocr Disord. 2014 Nov 26;14:91. doi: 10.1186/1472-6823-14-91.
9
Effects of fluticasone propionate, triamcinolone acetonide, prednisone, and placebo on the hypothalamic-pituitary-adrenal axis.
J Allergy Clin Immunol. 1999 Apr;103(4):622-9. doi: 10.1016/s0091-6749(99)70234-4.
10
Corticosteroids in acute severe asthma: effectiveness of low doses.
Thorax. 1992 Aug;47(8):584-7. doi: 10.1136/thx.47.8.584.
引用本文的文献
1
Investigation of a case of prednisolone malabsorption.
Postgrad Med J. 1979 Jun;55(644):421-2. doi: 10.1136/pgmj.55.644.421.
本文引用的文献
1
A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma.
J Clin Pathol. 1962 Jul;15(4):374-9. doi: 10.1136/jcp.15.4.374.
2
Steroid resistance in bronchial asthma.
Ann Intern Med. 1968 Sep;69(3):493-9. doi: 10.7326/0003-4819-69-3-493.
3
Investigation into use of drugs preceding death from asthma.
Br Med J. 1968 Feb 10;1(5588):339-43. doi: 10.1136/bmj.1.5588.339.
4
A study of cortisol metabolism in patients with chronic asthma.
Australas Ann Med. 1967 Nov;16(4):297-304. doi: 10.1111/imj.1967.16.4.297.
5
Intravenous corticosteroids in treatment of acute bronchial asthma.
Lancet. 1970 Nov 21;2(7682):1047-9. doi: 10.1016/s0140-6736(70)90283-7.
Zotero 插件