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Chymopapain C, an immunosuppressive protease. I. Partial purification and characterization.

作者信息

Clagett J A, Tokuda S, Engelhard W E

出版信息

Proc Soc Exp Biol Med. 1974 Apr;145(4):1250-7. doi: 10.3181/00379727-145-37991.

DOI:10.3181/00379727-145-37991
PMID:4827736
Abstract
摘要

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Chymopapain C, an immunosuppressive protease. I. Partial purification and characterization.木瓜凝乳蛋白酶C，一种免疫抑制蛋白酶。I. 部分纯化及特性鉴定
Proc Soc Exp Biol Med. 1974 Apr;145(4):1250-7. doi: 10.3181/00379727-145-37991.
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引用本文的文献

1
Cysteine protease cathepsin X modulates immune response via activation of beta2 integrins.半胱氨酸蛋白酶组织蛋白酶X通过激活β2整合素来调节免疫反应。
Immunology. 2008 May;124(1):76-88. doi: 10.1111/j.1365-2567.2007.02740.x. Epub 2008 Jan 11.
2
Structure of chymopapain M the late-eluted chymopapain deduced by comparative modelling techniques and active-centre characteristics determined by pH-dependent kinetics of catalysis and reactions with time-dependent inhibitors: the Cys-25/His-159 ion-pair is insufficient for catalytic competence in both chymopapain M and papain.糜蛋白酶M的结构：通过比较建模技术推导得出的晚期洗脱糜蛋白酶，以及通过pH依赖性催化动力学和与时间依赖性抑制剂反应确定的活性中心特征：半胱氨酸-25/组氨酸-159离子对对于糜蛋白酶M和木瓜蛋白酶的催化活性而言均不充分。
Biochem J. 1994 Jun 15;300 ( Pt 3)(Pt 3):805-20. doi: 10.1042/bj3000805.
3
Chymopapain. Chromatographic purification and immunological characterization.木瓜凝乳蛋白酶。色谱纯化及免疫学特性鉴定。
Biochem J. 1984 Oct 1;223(1):81-8. doi: 10.1042/bj2230081.
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A re-evaluation of the nomenclature of the cysteine proteinases of Carica papaya and a rational basis for their identification.番木瓜半胱氨酸蛋白酶命名的重新评估及其鉴定的合理依据。
Biochem J. 1983 Aug 1;213(2):559-60. doi: 10.1042/bj2130559.
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Affinity purification of the novel cysteine proteinase papaya proteinase IV, and papain from papaya latex.
Biochem J. 1989 Jul 15;261(2):469-76. doi: 10.1042/bj2610469.