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[急性白血病或再生障碍性贫血患者父母中HL-A抗原的相似性]

[Similarity of the HL-A antigens in parents of patients with acute leukemia or aplastic anemia].

作者信息

Werner-Favre C, von Fliedner W, Jeannet M

出版信息

Schweiz Med Wochenschr. 1979 Sep 29;109(37):1399.

PMID:482918
Abstract

The frequency of common HLA-A and -B antigens was determined in 30 couples with a child suffering from acute leukemia (AL), 34 couples with a child suffering from aplastic anemia (AA) and 58 random couples with healthy children. Increased frequency of couples sharing at least two common antigens was observed in parents of both AL and AA children.

摘要

对30对有患急性白血病(AL)孩子的夫妇、34对有患再生障碍性贫血(AA)孩子的夫妇以及58对有健康孩子的随机夫妇,测定了常见HLA - A和 - B抗原的频率。在患AL和AA孩子的父母中,均观察到共享至少两种共同抗原的夫妇频率增加。

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1
[Similarity of the HL-A antigens in parents of patients with acute leukemia or aplastic anemia].[急性白血病或再生障碍性贫血患者父母中HL-A抗原的相似性]
Schweiz Med Wochenschr. 1979 Sep 29;109(37):1399.
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Recipients of HLA-identical sibling marrow transplants with severe aplastic anemia engraft more quickly, and those with chronic myeloid leukemia more slowly, than those with acute leukemia.与急性白血病患者相比,患有严重再生障碍性贫血的 HLA 同型同胞骨髓移植受者植入更快,而患有慢性粒细胞白血病的受者植入更慢。
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