Wood M R, Cohen M J
Science. 1979 Oct 19;206(4416):344-7. doi: 10.1126/science.482943.
Identified reticulospinal neurons whose giant axons were severed after spinal cord transection were filled with horseradish peroxidase. Whole mounts and serial-section light and electron micrographs show axon regeneration across the spinal lesion and the formation of new synapses. Normal swimming activity returns in the spinally transected animals, although the regenerated synapses are in atypical regions of the spinal cord.
脊髓横断后，其粗大轴突被切断的已鉴定网状脊髓神经元用辣根过氧化物酶填充。整装片以及连续切片的光镜和电镜照片显示轴突再生穿过脊髓损伤部位并形成新的突触。脊髓横断的动物恢复了正常的游泳活动，尽管再生的突触位于脊髓的非典型区域。
