Chuich G A, Makovetskiĭ Iu V, Chernenko Iu P
Tsitologiia. 1979 Jul;21(7):775-80.
Rat liver specimens were deformed by compression between two parallel plates up to the state of plastic deformation to study with the electron microscope. The mechanical deformation was followed by a destruction of intercellular contacts and separation of hepatocytes. According to the pattern of destruction, all the contact elements can be divided into two groups. 1. Simple junction, desmosome, intermediate junction which exibit a wide range of structural changes prior to the moment of destruction. In this case, the process of cell separation proceeds in the adhesive way. 2. Tight and gap junctions which exibit a higher structural stability. In this case the process of cell separation appears to be of the cohesine nature.
将大鼠肝脏标本置于两块平行板之间进行压缩直至塑性变形状态，以便用电子显微镜进行研究。机械变形之后，细胞间接触遭到破坏，肝细胞分离。根据破坏模式，所有接触元件可分为两组。1. 简单连接、桥粒、中间连接，在破坏时刻之前会呈现出广泛的结构变化。在这种情况下，细胞分离过程以黏附方式进行。2. 紧密连接和缝隙连接，具有更高的结构稳定性。在这种情况下，细胞分离过程似乎具有凝聚性质。
