神经管缺陷的产前检测。甲胎蛋白与β-微量蛋白检测的比较。
Prenatal detection of neural tube defects. Comparison between alpha-fetoprotein and beta-trace protein assays.
作者信息
Milunsky A, Macri J N, Weiss R R, Alpert E, McIsaac D G, Joshi M S
出版信息
Am J Obstet Gynecol. 1975 Jun 1;122(3):313-5. doi: 10.1016/0002-9378(75)90175-1.
PMID:48343
Abstract
The prenatal diagnosis of neural tube defects is now possible in about 90 per cent of cases by assaying the amniotic fluid for alpha fetoprotein. The accuracy of beta-trace protein assays on amniotic fluid samples from defective fetuses was compared to alpha-fetoprotein studies. At present, alpha-fetoprotein studies provide more reliable results.
摘要
目前，通过检测羊水甲胎蛋白，约90%的神经管缺陷病例可实现产前诊断。将来自缺陷胎儿羊水样本的β-微量蛋白检测准确性与甲胎蛋白研究进行了比较。目前，甲胎蛋白研究提供了更可靠的结果。
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