大鼠青石棉诱发胸膜间皮瘤的放射学诊断

McLachlan M S, Wagner J C

Br J Exp Pathol. 1974 Apr;55(2):164-8.

Crocidolite asbestos dust was inoculated intrapleurally in 36 rats. Chest radiographs were obtained up to 120 weeks after inoculation. Radiological and pathological observations were compared. In 3 animals, in which mesotheliomata were suspected radiologically, no evidence of malignancy was observed on histological examination. A radiological diagnosis suggesting probable or definite malignancy was made in all 7 animals with histologically proven mesotheliomata.

将青石棉粉尘经胸膜内接种到36只大鼠体内。在接种后长达120周的时间内拍摄胸部X光片。对放射学和病理学观察结果进行比较。在3只经放射学检查怀疑患有间皮瘤的动物中，组织学检查未发现恶性肿瘤的证据。在所有7只经组织学证实患有间皮瘤的动物中，均做出了提示可能或肯定为恶性肿瘤的放射学诊断。