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大鼠青石棉诱发胸膜间皮瘤的放射学诊断

Radiological diagnosis of crocidolite induced pleural mesotheliomata in the rat.

作者信息

McLachlan M S, Wagner J C

出版信息

Br J Exp Pathol. 1974 Apr;55(2):164-8.

PMID:4835804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2072523/
Abstract

Crocidolite asbestos dust was inoculated intrapleurally in 36 rats. Chest radiographs were obtained up to 120 weeks after inoculation. Radiological and pathological observations were compared. In 3 animals, in which mesotheliomata were suspected radiologically, no evidence of malignancy was observed on histological examination. A radiological diagnosis suggesting probable or definite malignancy was made in all 7 animals with histologically proven mesotheliomata.

摘要

将青石棉粉尘经胸膜内接种到36只大鼠体内。在接种后长达120周的时间内拍摄胸部X光片。对放射学和病理学观察结果进行比较。在3只经放射学检查怀疑患有间皮瘤的动物中,组织学检查未发现恶性肿瘤的证据。在所有7只经组织学证实患有间皮瘤的动物中,均做出了提示可能或肯定为恶性肿瘤的放射学诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f5f/2072523/9fad4489b4a6/brjexppathol00404-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f5f/2072523/a8b1e3d32899/brjexppathol00404-0083-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f5f/2072523/6c5acea51d66/brjexppathol00404-0082-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f5f/2072523/9fad4489b4a6/brjexppathol00404-0081-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f5f/2072523/a8b1e3d32899/brjexppathol00404-0083-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f5f/2072523/6c5acea51d66/brjexppathol00404-0082-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f5f/2072523/9fad4489b4a6/brjexppathol00404-0081-a.jpg

相似文献

1
Radiological diagnosis of crocidolite induced pleural mesotheliomata in the rat.大鼠青石棉诱发胸膜间皮瘤的放射学诊断
Br J Exp Pathol. 1974 Apr;55(2):164-8.
2
[Malignant pleural mesothelioma of a female adult following exposure to asbestos in childhood].[一名成年女性在儿童期接触石棉后发生的恶性胸膜间皮瘤]
Prax Pneumol. 1970 Jan;24(1):39-45.
3
[Radiologic diagnosis in malignant pleural mesothelioma].[恶性胸膜间皮瘤的放射学诊断]
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Asbestos and malignant disease.
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Pleural mesothelioma.
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Radiological features of diffuse mesothelioma.弥漫性间皮瘤的放射学特征。
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Calcification in a pleural mesothelioma.胸膜间皮瘤中的钙化。
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Early malignant changes in pleural plaques due to asbestos exposure: a case report.
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引用本文的文献

1
Macrophage stimulation and the inflammatory response to asbestos.巨噬细胞刺激与对石棉的炎症反应。
Environ Health Perspect. 1980 Feb;34:69-74. doi: 10.1289/ehp.803469.
2
Suppression of the neutral protease activity of macrophages treated with asbestos in vitro.体外抑制石棉处理的巨噬细胞的中性蛋白酶活性。
Environ Health Perspect. 1983 Sep;51:103-8. doi: 10.1289/ehp.8351103.
3
Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids.巨噬细胞纤溶酶原激活剂:石棉诱导作用被抗炎类固醇阻断。

本文引用的文献

1
Mesotheliomas in rats following inoculation with asbestos.接种石棉后大鼠发生的间皮瘤。
Br J Cancer. 1969 Sep;23(3):567-81. doi: 10.1038/bjc.1969.70.
J Exp Med. 1976 Dec 1;144(6):1689-94. doi: 10.1084/jem.144.6.1689.