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甲状腺毒症中可逆性运动神经元功能障碍的证据。

Evidence for reversible motoneurone dysfunction in thyrotoxicosis.

作者信息

McComas A J, Sica R E, McNabb A R, Goldberg W M, Upton A R

出版信息

J Neurol Neurosurg Psychiatry. 1974 May;37(5):548-58. doi: 10.1136/jnnp.37.5.548.

DOI:10.1136/jnnp.37.5.548
PMID:4836749
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC494699/
Abstract

Motor unit estimating techniques have been employed as part of a comprehensive electrophysiological survey of peripheral nerve and muscle in 20 patients with thyrotoxicosis. In all patients there was evidence of a loss of operational motor units; the selective nature of this involvement suggested that the motoneurone soma was the site of the primary lesion. The reversible nature of the postulated motoneurone dysfunction was demonstrated by the increased motor unit counts in six patients who were studied again after treatment of their thyrotoxicosis.

摘要

运动单位估计技术已被用于对20例甲状腺毒症患者的周围神经和肌肉进行全面的电生理检查。所有患者均有有效运动单位减少的证据;这种受累的选择性表明运动神经元胞体是原发性病变的部位。6例甲状腺毒症患者在治疗后再次接受检查,其运动单位计数增加,证明了假定的运动神经元功能障碍的可逆性。

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Pathogenic SCN5A Mutation and Thyrotoxicosis-Related Neurological Syndrome: Casual or Causal Relationship?致病性SCN5A突变与甲状腺毒症相关神经综合征:偶然还是因果关系?
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Polyneuritis cranialis with generalized hyperreflexia as a presenting manifestation of thyrotoxicosis.以多发性颅神经病变伴全身反射亢进为首发表现的甲状腺毒症
Ann Indian Acad Neurol. 2015 Apr-Jun;18(2):240-2. doi: 10.4103/0972-2327.150625.

本文引用的文献

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Electromyographic and endocrine studies in chronic thyrotoxic myopathy.慢性甲状腺毒症性肌病的肌电图和内分泌研究
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A study of the ankle jerk in myxedema.黏液性水肿患者踝反射的研究。
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PERIPHERAL NERVE CHANGES IN ORTHO-CRESYL PHOSPHATE POISONING IN THE CAT.猫体内邻甲酚磷酸酯中毒时的周围神经变化
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Chronic thyrotoxic myopathy.慢性甲状腺毒症性肌病
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Polyradiculo-myopathia in transient thyrotoxicosis.
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Electrophysiological study of dystrophia myotonica.强直性肌营养不良的电生理研究
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Electrophysiological estimation of the number of motor units within a human muscle.人体肌肉内运动单位数量的电生理评估。
J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):121-31. doi: 10.1136/jnnp.34.2.121.