Anichkov N M, Zolotareva G A
Vopr Onkol. 1979;25(7):35-9.
Cytomorphometric examination of the normal urothelium, 3 primary, 3 recurrent papillomas of the urinary bladder and 3 cancers of stage I indicated that average relative volumes of the nucleus and cytoplasm in their cells are nearly similar. Since these bolumes increase simultaneously in the tumors concerned, there is no change in the "nucleus-cytoplasm correlation" or "index" described above. Cytomorphometric indices of the nucleus and cytoplasma in papillomas are more close to those of high-differentiated cancer than of the normal urothelium. In histologically indistinguishable primary and recurrent transitional cell papillomas the indices would differ: in primary papillomas compared with the norma the amount of mitochondria is reliably increased statistically, but the volume of each of them is diminished, whereas in recurrent ones--vice versa.
对正常尿路上皮、3例原发性膀胱乳头状瘤、3例复发性膀胱乳头状瘤以及3例I期膀胱癌进行细胞形态计量学检查，结果表明，这些病变细胞的细胞核与细胞质平均相对体积几乎相似。由于在相关肿瘤中这些体积同时增加，上述“细胞核 - 细胞质相关性”或“指数”没有变化。乳头状瘤细胞核和细胞质的细胞形态计量学指数比正常尿路上皮更接近高分化癌。在组织学上难以区分的原发性和复发性移行细胞乳头状瘤中，指数会有所不同：与正常情况相比，原发性乳头状瘤中线粒体数量在统计学上可靠增加，但每个线粒体的体积减小，而在复发性乳头状瘤中——情况相反。
