Chopra S K, Mohsenifar Z
West J Med. 1979 Jul;131(1):4-7.
Fiberoptic bronchoscopy (washings, brushings and biopsies) was done in 25 cases of proven opportunistic pulmonary infections in compromised hosts. Diagnostic yields of bronchoscopic procedures and expectorated sputum were compared. Sputum examination gave the lowest yield (14 percent). Bronchial washings and brushings were diagnostic in 30 percent and 38 percent of patients, respectively. On transbronchial biopsy of the lung (TBB) pathogens were identified in 75 percent of patients with Pneumocystis carinii infection and 67 percent of patients with other opportunistic infections. The overall TBB yield of 73 percent was superior (P<0.05) to that of either washings or brushings. The yield from combining washings and brushings was greater than from either procedure alone, but combination with TBB did not result in any significant improvement. TBB is recommended as a useful diagnostic procedure in patients with suspected opportunistic pulmonary infections. Morbidity was minimal with this procedure, and the need for thoracotomy was reduced when it was used.
对25例确诊为免疫功能低下宿主机会性肺部感染的患者进行了纤维支气管镜检查（冲洗、刷检和活检）。比较了支气管镜检查和咳出痰液的诊断阳性率。痰液检查的阳性率最低（14%）。支气管冲洗和刷检的诊断阳性率分别为30%和38%。在经支气管肺活检（TBB）中，卡氏肺孢子虫感染患者的病原体检出率为75%，其他机会性感染患者的病原体检出率为67%。TBB的总体阳性率为73%，优于冲洗或刷检（P<0.05）。冲洗和刷检联合应用的阳性率高于单独任何一种方法，但与TBB联合应用并未带来显著改善。对于疑似机会性肺部感染的患者，推荐TBB作为一种有用的诊断方法。该方法的并发症极少，使用该方法时开胸手术的需求也减少了。
