Marier G, MacFarland H, Wiberg G S, Buchwald H, Dussault P
Can Med Assoc J. 1974 Jul 6;111(1):39-42.
Measurement of blood fluorocarbon levels was carried out in subjects exposed to a number of household aerosol products containing fluorocarbon gases as propellants. All aerosols were used according to manufacturers' recommendations. The general purpose of the study was to determine whether with normal routine exposure to a wide variety of household aerosol products fluorocarbon could be found in the blood and if so, to check the potential toxicity of the levels reached. Daily exposure to aerosols according to the study regimen lasted four consecutive weeks; this period was preceded and followed by two weeks of abstention from exposure. At the end of each of the three periods a medical examination, including evaluation of cardiac function, respiratory function studies, and hematological and functional clinical biochemical tests was performed. All tests and assessments failed to show any indication of toxicity. No trace of fluorocarbon was found in any of the blood sampled at intervals during the study.
对接触多种含有氟碳气体作为推进剂的家用气雾剂产品的受试者进行了血液中氟碳水平的测量。所有气雾剂均按照制造商的建议使用。该研究的总体目的是确定在正常日常接触多种家用气雾剂产品的情况下，血液中是否能检测到氟碳，若能检测到，则检查所达到的水平的潜在毒性。根据研究方案，每日接触气雾剂持续四周；在此期间之前和之后各有两周不接触。在三个阶段的每个阶段结束时，都进行了一次医学检查，包括心脏功能评估、呼吸功能研究以及血液学和功能性临床生化测试。所有测试和评估均未显示出任何毒性迹象。在研究期间定期采集的任何血液样本中均未发现氟碳痕迹。
