King W A, Basrur P K
Acta Vet Scand. 1979;20(2):245-57. doi: 10.1186/BF03546616.
Biopsies of skeletal muscle collected from 24 animals classified as “double muscled” were examined by light and electron microscopy. The muscle samples exhibited degenerative changes including the presence of vacuolations and lamellated structures, fragmentation of myofibers, accumulation of glycogen granules, disruption of neuromuscular junctions and disorganization of the sarcolemma. In the light of the excessive fragility of the erythrocyte membranes noted previously, the alteration in the sarcolemma suggests that a generalized cell membrane defect may be the most consistent feature of the “double muscling syndrome” in cattle.
对从24只被归类为“双肌”的动物身上采集的骨骼肌活检样本进行了光镜和电镜检查。肌肉样本呈现出退行性变化，包括空泡化和层状结构的出现、肌纤维断裂、糖原颗粒堆积、神经肌肉接头破坏以及肌膜紊乱。鉴于先前观察到的红细胞膜过度脆弱，肌膜的改变表明，普遍的细胞膜缺陷可能是牛“双肌综合征”最一致的特征。
