Bergmann V, Kursa J
Arch Exp Veterinarmed. 1979 Jan;33(1):1-12.
Electron microscopy was used to examine the sekeletal muscles of young cattle, aged between 13 and 24 months, with spontaneous enzootic myodystrophy (nutritional myodegeneration due to selenium deficiency, white muscle disease). The animals had been received from Sumava District, Southern Bohemia, an area known for shortage of selenium. Outbreaks of clinical illness were recorded from them between four and 18 days from the beginning of grazing. Most of the ultrastructural changes included decomposition of myofibrils and hyalinisation of fibres as well as defective fibril synthesis (Z-striation abnormality), some of the latter phenomena recordable even from regenerating fibre. However, minor disorders only were established from the mitochondria, sarcoplasmic reticulum, components of sarcoplasm, and vessels. There were far-reaching ultrastructural similarities to nutritional myodegeneration of sheep. The changes recorded are likely to suggest a specific role played by selenium in the formation and preservation of myofibril proteins.
采用电子显微镜检查了13至24月龄患有自发性地方流行性肌营养不良（因硒缺乏导致的营养性肌变性，即白肌病）的幼牛骨骼肌。这些动物来自波希米亚南部的苏马瓦地区，该地区以缺硒著称。从开始放牧起4至18天内记录到它们出现临床疾病暴发。大多数超微结构变化包括肌原纤维分解、纤维玻璃样变以及原纤维合成缺陷（Z线异常），其中一些后者现象甚至在再生纤维中也可记录到。然而，仅在线粒体、肌浆网、肌浆成分和血管中发现了轻微病变。与绵羊营养性肌变性存在深远的超微结构相似性。记录到的这些变化可能表明硒在肌原纤维蛋白的形成和维持中发挥了特定作用。
