神经病和运动神经元疾病中人类运动单位的收缩和电特性
Contractile and electrical properties of human motor units in neuropathies and motor neurone disease.
作者信息
Milner-Brown H S, Stein R B, Lee R G
出版信息
J Neurol Neurosurg Psychiatry. 1974 Jun;37(6):670-6. doi: 10.1136/jnnp.37.6.670.
Abstract
The contractile and electrical properties of motor units in the first dorsal interosseous muscle of the hand have been studied in 26 patients with ulnar neuropathies and motor neurone disease (amyotrophic lateral sclerosis). Among patients with unilateral pressure or entrapment ulnar neuropathies, there was a tendency for the twitch tensions for single motor units to be smaller, while the surface EMG amplitudes were generally larger in the affected hands. Very large EMG amplitudes but normal size twitch tensions were observed among the motor neurone disease patients, indicating that, in general, motor units enlarged by sprouting are less efficient contractile units than units of normal physiological size.
摘要
对26例尺神经病变和运动神经元病（肌萎缩侧索硬化症）患者手部第一背侧骨间肌运动单位的收缩和电特性进行了研究。在单侧压迫或卡压性尺神经病变患者中，单个运动单位的抽搐张力往往较小，而患侧手部的表面肌电图（EMG）振幅通常较大。在运动神经元病患者中观察到非常大的EMG振幅，但抽搐张力大小正常，这表明一般来说，通过出芽扩大的运动单位作为收缩单位的效率低于正常生理大小的单位。
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