Hachamovitch M, Bracken M B, Simons H
Am J Obstet Gynecol. 1979 Oct 1;135(3):327-30. doi: 10.1016/0002-9378(79)90699-9.
This study examines the effect of laminaria and oxytocin in 638 saline instillation abortions. Laminaria were inserted into the cervical canal in the physician's office 2 to 3 hours before admission to hospital for instillation. Pitocin was given intravenously at a rate of 417 to 555 mu/min starting 2 hours after instillation. Pitocin was given intravenously at a rate of 417 to 555 mu/min starting 2 hours after instillation. Center for Disease Control (CDC) criteria were used to define complications in the present series. Complication rates compared favorably to those in a national CDC study of traditional saline procedures. Instillation-abortion times averaged 12.5 hours in the present series, about half the time previously reported for saline abortion. If confirmed by other studies, laminaria and oxytocin will be beneficial adjuncts for managing patients aborted by saline instillation.
本研究调查了海藻棒和缩宫素在638例羊膜腔内注入生理盐水引产中的作用。在入院进行羊膜腔内注入生理盐水前2至3小时，在医生办公室将海藻棒插入宫颈管。注入生理盐水2小时后，静脉注射缩宫素，速度为每分钟417至555毫单位。注入生理盐水2小时后，静脉注射缩宫素，速度为每分钟417至555毫单位。本研究系列采用疾病控制中心（CDC）的标准来定义并发症。与疾病控制中心一项关于传统羊膜腔内注入生理盐水引产的全国性研究相比，本研究系列的并发症发生率更优。本研究系列中，羊膜腔内注入生理盐水引产的平均时间为12.5小时，约为之前报道的羊膜腔内注入生理盐水引产时间的一半。如果其他研究证实，海藻棒和缩宫素将成为处理羊膜腔内注入生理盐水引产患者的有益辅助手段。
