单体甲基丙烯酸甲酯对眼组织的影响。

Effects of monomeric methylmethacrylate on ocular tissues.

作者信息

Holyk P R, Eifrig D E

出版信息

Am J Ophthalmol. 1979 Sep;88(3 Pt 1):385-95. doi: 10.1016/0002-9394(79)90638-x.

Abstract

Toxic effects of high doses of monomeric methylmethacrylate were demonstrated in rabbit eyes. These effects were not related to surgical manipulation. Monomeric methylmethacrylate caused limbal hyperemia, corneal edema, corneal neovascularization, iris engorgement, anterior chamber inflammation, iris atrophy, and cataract. The doses of monomeric methylmethacrylate needed to produce these lesions were much higher than the amount of monomer available for leaching out of implanted intraocular lenses.

摘要

高剂量的甲基丙烯酸甲酯单体对兔眼有毒性作用。这些作用与手术操作无关。甲基丙烯酸甲酯单体可导致角膜缘充血、角膜水肿、角膜新生血管形成、虹膜充血、前房炎症、虹膜萎缩和白内障。产生这些病变所需的甲基丙烯酸甲酯单体剂量远高于可从植入的人工晶状体中浸出的单体量。