Warren K S, Mahmoud A A, Muruka J F, Whittaker L R, Ouma J H, Arap Siongok T K
Am J Trop Med Hyg. 1979 Sep;28(5):864-70.
Several studies of schistosomiasis haematobia in Africa have revealed a correlation between intensity of infection as measured by urine egg counts and severity of disease as determined by intravenous pyelography. The present study consisted of a survey of 390 school children in the coastal area of Kenya involving a single egg count, and intravenous pyelograms in a stratified random sample of 69 children; the results showed a greater prevalence of urinary tract disease in those with higher intensities of infection. This survey was then followed by a more detailed study in which nine consecutive daily egg counts were done on 121 children; 17 of these children, subdivided into three groups with different intensities in infection, were given intravenous pyelograms. The results were similar in the 11 children with minimal and moderate counts (averaging, respectively, less than 1 egg and 167 eggs/10 ml urine daily), with approximately 30% having bladder or renal abnormalities. In comparison, all of the six children with heavy counts (averaging 1,288 eggs/10 ml urine daily) had bladder lesions and five of them had renal lesions.
非洲几项关于埃及血吸虫病的研究表明，通过尿卵计数衡量的感染强度与通过静脉肾盂造影确定的疾病严重程度之间存在关联。本研究对肯尼亚沿海地区的390名学童进行了调查，包括一次卵计数，并对69名儿童的分层随机样本进行了静脉肾盂造影；结果显示，感染强度较高的儿童尿路疾病患病率更高。此次调查之后又进行了一项更详细的研究，对121名儿童连续九天每日进行卵计数；其中17名儿童根据感染强度分为三组，接受了静脉肾盂造影。卵计数最少和中等的11名儿童（平均每日分别少于1个卵和167个卵/10毫升尿液）的结果相似，约30%有膀胱或肾脏异常。相比之下，卵计数高的六名儿童（平均每日1288个卵/10毫升尿液）均有膀胱病变，其中五人有肾脏病变。
