人类免疫球蛋白G亚类的圆二色光谱比较。
A comparison of the circular dichroism spectra of the subclasses of human immunoglobulin G.
作者信息
Johnson P M, Scopes P M, Tracey B M, Watkins J
出版信息
Immunology. 1974 Jul;27(1):27-31.
Abstract
We have determined the circular dichroism of sixteen human IgG myeloma proteins representative of the four subclasses. No significant variation in β structure was observed between the subclasses. However, at wavelengths greater than 230 nm, the spectra of IgG3 myeloma proteins is quite distinct, indicating a unique conformation. Myeloma proteins of the other subclasses gave similar overall spectra, but some of the features of the negative maxima in the region of 260–280 nm appeared to be subclass-specific.
摘要
我们已经测定了代表四个亚类的16种人IgG骨髓瘤蛋白的圆二色性。各亚类之间未观察到β结构的显著差异。然而，在波长大于230nm时，IgG3骨髓瘤蛋白的光谱非常独特，表明其具有独特的构象。其他亚类的骨髓瘤蛋白给出了相似的整体光谱，但在260-280nm区域负峰的一些特征似乎具有亚类特异性。
相似文献
1
A comparison of the circular dichroism spectra of the subclasses of human immunoglobulin G.人类免疫球蛋白G亚类的圆二色光谱比较。
Immunology. 1974 Jul;27(1):27-31.
2
Three states of the pFh-fragment (Hinge region) from human myeloma IgG3 Kuc with native-like secondary structure.
Biochemistry (Mosc). 2000 Oct;65(10):1227-30.
3
[Structural peculiarities of protein typical of G-myelomas].
Ukr Biokhim Zh. 1976 Jan-Feb;48(1):78-81.
4
[Comparative investigation of the dynamic conformational properties of human myeloma immunoglobulin G of different subclasses using impulse NMR].
Mol Biol (Mosk). 1983 Jul-Aug;17(4):734-40.
5
Comparison of the circular dichroism spectra of the subclasses of human immunoglobulin A.
FEBS Lett. 1976 Jan 15;61(2):243-6. doi: 10.1016/0014-5793(76)81048-4.
6
[Calculation of the secondary structure of proteins from their circular dichroism spectra].
Biofizika. 1980 Mar-Apr;25(2):334-6.
7
[Structure of polyclonal and monoclonal immunoglobulins analysed by spectropolarimetric figures].[通过旋光光谱图分析多克隆和单克隆免疫球蛋白的结构]
Verh Dtsch Ges Inn Med. 1971;77:777-80.
8
9
[Simultaneous calculation of the secondary structure and one of the reference spectra according to the protein circular dichroism].
Biofizika. 1980 May-Jun;25(3):561-2.
引用本文的文献
1
Biophysical characterization of the olfactomedin domain of myocilin, an extracellular matrix protein implicated in inherited forms of glaucoma.肌球蛋白外胚层结构域的生物物理特性，该蛋白是一种细胞外基质蛋白，与遗传性青光眼有关。
PLoS One. 2011 Jan 24;6(1):e16347. doi: 10.1371/journal.pone.0016347.
本文引用的文献
1
Structural studies of immunoglobulin G.免疫球蛋白G的结构研究。
Nature. 1969 Jan 11;221(5176):145-8. doi: 10.1038/221145a0.
2
Circular dichroism of Bence-Jones proteins and immunoglobulins G.
J Biochem. 1968 May;63(5):654-60. doi: 10.1093/oxfordjournals.jbchem.a128825.
3
Conformational differences of immunoglobulin G subclasses.免疫球蛋白G亚类的构象差异。
Biochim Biophys Acta. 1970 Nov 17;221(2):399-402. doi: 10.1016/0005-2795(70)90287-4.
4
Circular dichroism studies on the acid denaturation of gamma-immunoglobulin G and its fragments.γ-免疫球蛋白G及其片段酸变性的圆二色性研究
Biochemistry. 1970 Mar 3;9(5):1066-73. doi: 10.1021/bi00807a003.
5
The papain susceptibility of IgG myeloma proteins of different heavy chain subclasses.不同重链亚类的IgG骨髓瘤蛋白对木瓜蛋白酶的敏感性
Immunochemistry. 1970 Jan;7(1):1-6. doi: 10.1016/0019-2791(70)90025-x.
6
Circular dichroism of biological macromolecules.生物大分子的圆二色性
Science. 1966 Dec 9;154(3754):1288-99. doi: 10.1126/science.154.3754.1288.
7
Conformational studies on the tryptic digestion fragments of human immunoglobulin G.人免疫球蛋白G胰蛋白酶消化片段的构象研究
Arch Biochem Biophys. 1971 May;144(1):384-93. doi: 10.1016/0003-9861(71)90491-7.
8
The unique molecular weight of the heavy chain from human IgG3.人IgG3重链的独特分子量。
J Immunol. 1971 Jul;107(1):298-301.
9
Conformational changes accompanying the dissociation and association of immunoglobulin-G subunits.
Biochim Biophys Acta. 1972 Mar 15;263(1):70-81. doi: 10.1016/0005-2795(72)90160-2.
10
Proceedings: Differences in serum IgG structure in health and rheumatoid arthritis as studied by circular dichroic spectra.论文集：通过圆二色光谱研究健康人和类风湿关节炎患者血清IgG结构的差异。
Ann Rheum Dis. 1974 Jan;33(1):108. doi: 10.1136/ard.33.1.108-a.
Zotero 插件