采用带荧光检测的高压液相色谱法对尿液中的吗啡进行表征和定量分析。
Characterisation and quantitation of morphine in urine using high-pressure liquid chromatography with fluorescence detection.
作者信息
Jane I, Taylor J F
出版信息
J Chromatogr. 1975 Jun 4;109(1):37-42. doi: 10.1016/s0021-9673(01)81015-3.
PMID:48517
Abstract
A simple and rapid method for the identification and quantitation of morphine in urine samples is described. The procedure, which involves conversion of the drug a fluorescent product followed by liquid chromatography, is shown to be highly sensitive and specific. Levels down to 0.01 mug/ml of morphine can be quantitatively detected in urine. A large number of drugs have been tested and shown not to interfere.
摘要
本文描述了一种用于尿液样本中吗啡鉴定和定量的简单快速方法。该方法包括将药物转化为荧光产物，然后进行液相色谱分析，结果表明该方法具有高度的灵敏度和特异性。尿液中低至0.01微克/毫升的吗啡水平都可以进行定量检测。大量药物已经过测试，结果显示不会产生干扰。
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