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血清C反应蛋白检测在脑积水脑脊液分流术感染性并发症诊断中的应用

Serum C-reactive protein test in diagnosis of septic complications of cerebrospinal fluid shunts for hydrocephalus.

作者信息

Bayston R

出版信息

Arch Dis Child. 1979 Jul;54(7):545-8. doi: 10.1136/adc.54.7.545.

Abstract

Serial tests for serum C-reactive protein (CRP) were carried out on 40 children undergoing cerebrospinal fluid shunt surgery, to determine the pattern of appearance and disappearance of CRP in relation to this type of operation, in the absence of postoperative complications. Samples of sera from a further 268 children, 79 of whom presented after shunt surgery with symptoms suggesting infective complications related to the shunt, were examined for CRP. The results showed that, while the test in negative in uncomplicated colonisation of ventriculo-atrial shunts, it is reliably positive in patients with colonised ventriculo-peritoneal shunts, ventriculitis, or shunt nephritis.

摘要

对40名接受脑脊液分流手术的儿童进行了血清C反应蛋白(CRP)的系列检测,以确定在无术后并发症的情况下,CRP相对于此类手术的出现和消失模式。对另外268名儿童的血清样本进行了CRP检测,其中79名儿童在分流手术后出现了提示与分流相关的感染性并发症的症状。结果表明,虽然该检测在心室-心房分流无并发症定植时呈阴性,但在心室-腹腔分流定植、脑室炎或分流性肾炎患者中呈可靠阳性。

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本文引用的文献

9
Serological surveillance of children with CSF shunting devices.
Dev Med Child Neurol Suppl. 1975(35):104-10. doi: 10.1111/j.1469-8749.1975.tb03588.x.

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