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睾丸精原细胞瘤放疗后发生胃皮肤瘘。

Gastrocutaneous fistula following radiation therapy for seminoma of the testis.

作者信息

Hothem A L, Newsome J F

出版信息

Ann Surg. 1974 Sep;180(3):323-8. doi: 10.1097/00000658-197409000-00012.

DOI:10.1097/00000658-197409000-00012
PMID:4852138
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1343667/
Abstract

A case presentation of a gastrocutaneous fistula following orthovoltage radiotherapy for prophylactic lymph node sterilization for seminoma of the testis is recorded. Many factors determine the response of an organ to radiation and with certain circumstances irreversible damage ensues. The pathologic effects of radiation on the stomach in the reported patient illustrates two stages of injury, acute and chronic. The insidious course of chronic injury eventually destroyed gastric and abdominal wall tissue to create a gastrocutaneous fistula 45 months after radiotherapy. Radiation therapy is a critical therapeutic modality in the treatment of neoplastic diseases and should be carefully administered with close followup of patients for acute and latent radiation effects.

摘要

记录了一例睾丸精原细胞瘤预防性淋巴结清除术后采用深部X线放疗导致胃肠皮肤瘘的病例。许多因素决定器官对辐射的反应，在某些情况下会发生不可逆损伤。所报道患者中辐射对胃的病理影响说明了损伤的两个阶段，即急性和慢性。慢性损伤的隐匿过程最终破坏了胃和腹壁组织，在放疗45个月后形成了胃肠皮肤瘘。放射治疗是肿瘤疾病治疗中的关键治疗方式，应对患者进行仔细治疗并密切随访，以观察急性和潜在的放射效应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/1bc532fe80d6/annsurg00295-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/8045f1a788c4/annsurg00295-0076-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/a4b3e8ed03fb/annsurg00295-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/c47cad8670d6/annsurg00295-0077-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/4afa40c95014/annsurg00295-0077-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/dcab8e924825/annsurg00295-0078-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/85073f1dad6e/annsurg00295-0078-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/7b329c4e232f/annsurg00295-0078-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/190f3f1b9ec9/annsurg00295-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/44bd58b5110c/annsurg00295-0079-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/1bc532fe80d6/annsurg00295-0080-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/8045f1a788c4/annsurg00295-0076-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/251702e29ad9/annsurg00295-0076-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/0ebb256f7caf/annsurg00295-0076-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/a4b3e8ed03fb/annsurg00295-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/c47cad8670d6/annsurg00295-0077-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/4afa40c95014/annsurg00295-0077-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/dcab8e924825/annsurg00295-0078-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/85073f1dad6e/annsurg00295-0078-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/7b329c4e232f/annsurg00295-0078-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/190f3f1b9ec9/annsurg00295-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/44bd58b5110c/annsurg00295-0079-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53f6/1343667/1bc532fe80d6/annsurg00295-0080-a.jpg

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本文引用的文献

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Pathology and Pathologic Diagnosis of Radiation Lesions in the Gastro-Intestinal Tract.胃肠道放射性损伤的病理学及病理诊断
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Perforation of a gastric ulcer following intensive radiation therapy.
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RADIATION INJURY TO THE INTESTINAL TRACT.肠道的辐射损伤
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Gastrocutaneous fistula: etiology and treatment.胃皮肤瘘：病因与治疗
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Gastric ulceration following cobalt teletherapy. Estimation of the tolerance dose.钴远距离治疗后的胃溃疡。耐受剂量的估计。
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Surgery for radiation-damaged bowel.放射性损伤肠道的手术治疗。
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