Hamilton C, Horwich A, Easton D, Peckham M J
Radiother Oncol. 1986 Jun;6(2):115-20. doi: 10.1016/s0167-8140(86)80017-2.
The results of treatment by infradiaphragmatic lymph node irradiation and orchiectomy in 232 patients with Stage I testicular seminoma seen between 1963 and 1983 are reported. Of this group, only five (2%) patients relapsed and none died from seminoma. Contralateral testicular tumours occurred in 12 patients and five developed second non-testicular malignancies. The acute and late morbidity of radiotherapy was low although 15 patients developed peptic ulceration. There was a significant association between prior abdominal surgery and a history of dyspepsia with ensuing peptic ulceration. Future management policy is discussed on the basis of these observations.
报告了1963年至1983年间收治的232例I期睾丸精原细胞瘤患者经膈下淋巴结照射及睾丸切除术的治疗结果。该组中，仅5例（2%）患者复发，无1例死于精原细胞瘤。12例患者发生对侧睾丸肿瘤，5例发生第二种非睾丸恶性肿瘤。放疗的急性和晚期发病率较低，尽管有15例患者发生消化性溃疡。既往腹部手术与消化不良病史及随后发生的消化性溃疡之间存在显著关联。基于这些观察结果讨论了未来的管理策略。
