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A-NWS HONi(HON1)流感病毒在温度升高时的繁殖能力与嗜神经活性之间的联系。

Linkage between reproductive capacity at increased temperature and neurotropic activity in A-NWS HONi (HON1) influenza virus.

作者信息

Svobodová J, Tucková E, Vonka V

出版信息

Infect Immun. 1974 Aug;10(2):400-1. doi: 10.1128/iai.10.2.400-401.1974.

Abstract

We investigated the rate of covariation between the ability of the NWS strain of influenza virus to reproduce at increased temperature and its neurotropic properties. Results indicated that increased growth at 39 C was related to increased neurovirulence, and acquisition of the temperature-sensitive character was related to loss of neurovirulence.

摘要

我们研究了流感病毒NWS株在温度升高时的繁殖能力与其嗜神经特性之间的协变率。结果表明,在39℃时生长增加与神经毒力增加有关,而温度敏感性特征的获得与神经毒力丧失有关。

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本文引用的文献

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Virulence of temperature-sensitive mutants of influenza virus.
Br Med J. 1969 Sep 27;3(5673):757-8. doi: 10.1136/bmj.3.5673.757.

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