Svobodová J, Tucková E, Vonka V
Infect Immun. 1974 Aug;10(2):400-1. doi: 10.1128/iai.10.2.400-401.1974.
We investigated the rate of covariation between the ability of the NWS strain of influenza virus to reproduce at increased temperature and its neurotropic properties. Results indicated that increased growth at 39 C was related to increased neurovirulence, and acquisition of the temperature-sensitive character was related to loss of neurovirulence.
我们研究了流感病毒NWS株在温度升高时的繁殖能力与其嗜神经特性之间的协变率。结果表明,在39℃时生长增加与神经毒力增加有关,而温度敏感性特征的获得与神经毒力丧失有关。