Mechanism of action of coumarins. Significance of vitamin K epoxide.
作者信息
Sadowski J A, Suttie J W
出版信息
Biochemistry. 1974 Aug 27;13(18):3696-9. doi: 10.1021/bi00715a012.
PMID:4853124
Abstract
摘要
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Warfarin and vitamin K compete for binding to Phe55 in human VKOR.华法林和维生素 K 竞争结合人 VKOR 中的 Phe55。
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Purification of a vitamin K epoxide reductase that catalyzes conversion of vitamin K 2,3-epoxide to 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone.一种催化维生素K 2,3-环氧化物转化为3-羟基-2-甲基-3-植基-2,3-二氢萘醌的维生素K环氧化物还原酶的纯化。
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