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导管结垢问题。

The problem of catheter encrustation.

作者信息

Bruce A W, Sira S S, Clark A F, Awad S A

出版信息

Can Med Assoc J. 1974 Aug 3;111(3):238-9 passim.

PMID:4855013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1947672/
Abstract

Catheter encrustation was studied in a group of long-stay hospital patients using both latex and silicone catheters. Moisture accounted for 80% by weight of the encrusted material with both catheters. Of the dry weight 90% was composed of protein, calcium, phosphorus, magnesium and uric acid. No relationship was found between the amounts of these substances in the urine and in the encrusted material. High levels of calcium, phosphorus and magnesium were found in the encrusted material from patients infected with Proteus organisms. No direct relationship was found between the duration of catheter drainage and the degree of encrustation, and there was a variation in patient susceptibility to encrustation irrespective of the catheter material. There was significantly less encrustation associated with silicone catheters.

摘要

在一组长期住院患者中,对使用乳胶导管和硅胶导管的患者进行了导管结壳情况研究。两种导管结壳物质的重量中,水分占80%。干重的90%由蛋白质、钙、磷、镁和尿酸组成。尿液中这些物质的含量与结壳物质中的含量之间未发现相关性。感染变形杆菌的患者的结壳物质中发现钙、磷和镁含量很高。未发现导管引流持续时间与结壳程度之间存在直接关系,并且无论导管材料如何,患者对结壳的易感性存在差异。与硅胶导管相关的结壳明显较少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4839/1947672/a4dae7dd94cb/canmedaj01587-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4839/1947672/a4dae7dd94cb/canmedaj01587-0036-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4839/1947672/a4dae7dd94cb/canmedaj01587-0036-a.jpg

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本文引用的文献

1
The recognition and isolation from urine and serum of a peptide inhibitor to calcification.从尿液和血清中识别并分离出一种钙化肽抑制剂。
Johns Hopkins Med J. 1967 Mar;120(3):119-36.
2
A urinary peptide with extraordinary inhibitory powers against biological "calcification" (deposition of hydroxyapatite crystals).一种对生物“钙化”(羟基磷灰石晶体沉积)具有非凡抑制能力的尿肽。
Trans Assoc Am Physicians. 1966;79:137-45.
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Control of crystallization in urine.
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细菌生物膜与导管:理解导管相关性尿路感染中细菌策略的关键
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Physical, biochemical, and immunological characterization of a thermostable amidase from Klebsiella pneumoniae NCTR 1.肺炎克雷伯菌NCTR 1中一种耐热酰胺酶的物理、生化及免疫学特性
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A 4.6 kb DNA region of Rhizobium meliloti involved in determining urease and hydrogenase activities carries the structural genes for urease (ureA, ureB, ureC) interrupted by other open reading frames.苜蓿根瘤菌中一个参与决定脲酶和氢化酶活性的4.6 kb DNA区域携带脲酶的结构基因(ureA、ureB、ureC),这些结构基因被其他开放阅读框打断。
Mol Gen Genet. 1994 Mar;242(5):539-50. doi: 10.1007/BF00285277.
7
Randomized double-blind study of prophylactic methenamine hippurate treatment of patients with indwelling catheters.对留置导尿管患者进行马尿酸乌洛托品预防性治疗的随机双盲研究。
Eur J Clin Pharmacol. 1980 Nov;18(6):497-500. doi: 10.1007/BF00874662.
8
Antimicrobial prophylaxis in urology and transplantation.泌尿外科与移植领域的抗菌预防
World J Surg. 1982 May;6(3):281-92. doi: 10.1007/BF01653543.
9
Urease-positive bacteriuria and obstruction of long-term urinary catheters.脲酶阳性菌尿与长期导尿管梗阻
J Clin Microbiol. 1987 Nov;25(11):2216-7. doi: 10.1128/jcm.25.11.2216-2217.1987.
10
Microbial ureases: significance, regulation, and molecular characterization.微生物脲酶:意义、调控及分子特征
Microbiol Rev. 1989 Mar;53(1):85-108. doi: 10.1128/mr.53.1.85-108.1989.
4
Urethral reaction to foreign objects.尿道对外来物体的反应。
J Urol. 1971 Aug;106(2):227-30. doi: 10.1016/s0022-5347(17)61264-3.
5
Encrustation of catheter materials in vitro.导管材料的体外结痂
J Urol. 1972 Sep;108(3):473. doi: 10.1016/s0022-5347(17)60777-8.