Moreno Pardo B, Ferrutxe Frau J, Llopis Mínguez B, Baixauli Martínez J M, Moreno Barrachina E
Arch Esp Urol. 1979 Jul-Aug;32(4):309-24.
A study is made of 25 patients suffering from a vesicular prostate pathology causing sterility. We have assessed the age, profession, symptoms, genital exploration and ejaculation study including the amount, pH, visocity, fructose, ascorbic acid, count, motility and morphology of the sperms and the high leukocyte reading. A seminal liquid culture has been carried out on 21 patients, alone or in association with cultures of prostate and urine secretion following prostate massaging with positive results in 16 of them (76%). Treatment was begun on 22 patients, in 13 of whom the results are known. Spermiogram readings became normal in 5 (38%) with one pregnancy; there was an associated pathology in the wife in 3 cases. As antibacterians we have basically used trimetoprim-sulphametoxazol associated with erythromycin or not and sometimes, according to the antibogram, with other antibiotics, as well as drugs to clear the prostate area. The best results were obtained in astenozoospermias. The effectiveness of the treatment was equally due to the use of TMP-SMZ on its own or along with erythromycin. The other drugs have not improved the results, except for minocyclin which megativated a sperm culture. As a preliminary result the author presented three patients with sperm infection produced by E. coli at whom the titer of antibodies in serum was investigated.
对25例患有导致不育的前列腺水疱性病变的患者进行了研究。我们评估了患者的年龄、职业、症状、生殖器检查以及射精研究，包括精液量、pH值、粘度、果糖、抗坏血酸、精子计数、活力和形态以及高白细胞读数。对21例患者进行了精液培养，单独进行或在前列腺按摩后与前列腺和尿液分泌物培养联合进行，其中16例（76%）结果呈阳性。对22例患者开始治疗，其中13例的治疗结果已知。5例（38%）患者的精子图读数恢复正常，并有1例怀孕；3例患者的妻子存在相关病理情况。作为抗菌药物，我们主要使用了甲氧苄啶 - 磺胺甲恶唑，可联合或不联合红霉素，有时根据药敏试验结果，还会使用其他抗生素，以及用于清理前列腺区域的药物。在弱精子症患者中取得了最佳治疗效果。治疗效果同样归因于单独使用甲氧苄啶 - 磺胺甲恶唑或与红霉素联合使用。除米诺环素使精子培养转阴外，其他药物并未改善治疗结果。作为初步结果，作者展示了3例由大肠杆菌引起精子感染的患者，并对其血清中的抗体滴度进行了研究。
