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细菌学治愈后,感染无症状不育男性精液质量的改善。

Improvement of semen quality in infected asymptomatic infertile male after bacteriological cure.

作者信息

Cardoso E M, Santoianni J E, De Paulis A N, Andrada J A, Predari S C, Arregger A L

机构信息

Departmento de Endocrinologia, Facultad de Medicina, Universidad de Buenos Aires, Argentina.

出版信息

Medicina (B Aires). 1998;58(2):160-4.

PMID:9706249
Abstract

Bacteriological etiology was investigated in 29 infected asymptomatic infertile males. The localization of the infection and the effect of a long term antibiotic therapy on semen parameters were evaluated. The most frequent etiological agent isolated was Enterococcus faecalis. Positive bacteriological culture was obtained in prostatic fluid in 16 patients and in semen in 13. Bacteriological cure was achieved in 24 cases and it was associated with improved seminal parameters: sperm concentration, viability and total motile sperm per ejaculate. In 5 patients without bacteriological cure there was no change in semen analysis after antibiotic therapy. In 45% of the infected patients there were less than 0.5 x 10(6)/ml seminal polymorphonuclear leukocytes. In view of these findings granulocyte concentration seems to be a poor marker to predict infection.

摘要

对29名感染的无症状不育男性进行了细菌学病因调查。评估了感染的部位以及长期抗生素治疗对精液参数的影响。分离出的最常见病原体是粪肠球菌。16例患者前列腺液细菌培养阳性,13例精液细菌培养阳性。24例实现了细菌学治愈,且与精液参数改善相关:精子浓度、活力和每次射精的总活动精子数。5例未实现细菌学治愈的患者,抗生素治疗后精液分析无变化。45%的感染患者精液多形核白细胞少于0.5×10⁶/ml。鉴于这些发现,粒细胞浓度似乎是预测感染的不良指标。

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