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关于小鼠皮肤表面脂质在曼氏血吸虫尾蚴“体内”穿透中作用的新思考(作者译)

[New considerations on the role of the mouse skin surface lipids on the "in vivo" penetration of "Schistosoma mansoni" cercariae (author's transl)].

作者信息

Simoni L, Bianchini C

出版信息

Ann Sclavo. 1979 Jan-Feb;21(1):88-92.

PMID:485595
Abstract

The authors have studied the effect of delipitizing and of the previously extracted skin lipids reapplication on mice experimental infected with Schistosoma mansoni cercariae. The results demonstrated that the amount of living cercariae, not penetrated, recovered after the exposition to the parasite is greater in the delipitized mice than in the other ones. The low amount of worms recovered from the treated mice might be due to the effect of the mouse skin surface lipids not only on stimulating cercarial penetration but also on allowing cercarial transformation to schistosomula during skin crossing.

摘要

作者研究了去脂以及重新涂抹先前提取的皮肤脂质对感染曼氏血吸虫尾蚴的实验小鼠的影响。结果表明,暴露于寄生虫后未穿透的活尾蚴数量,去脂小鼠比其他小鼠更多。从处理过的小鼠体内回收的蠕虫数量较少,可能是由于小鼠皮肤表面脂质不仅具有刺激尾蚴穿透的作用,还能使尾蚴在穿过皮肤过程中转变为血吸虫幼虫。

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