• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

大鼠边缘叶皮质中的多巴胺神经末梢：精神分裂症多巴胺假说的相关方面

Dopamine nerve terminals in the rat limbic cortex: aspects of the dopamine hypothesis of schizophrenia.

作者信息

Hökfelt T, Ljungdahl A, Fuxe K, Johansson O

出版信息

Science. 1974 Apr 12;184(4133):177-9. doi: 10.1126/science.184.4133.177.

DOI:10.1126/science.184.4133.177
PMID:4856104
Abstract

The existence of cortical dopamine nerve terminals is demonstrated with a highly sensitive modification of the Falck-Hillarp fluorescence technique. This confirms previous biochemical reports of high dopamine levels in the cortex. The histochemistry reveals that the distribution is regional and confined to the limbic cortex.

摘要

通过对法尔克-希拉尔普荧光技术的高度灵敏改进，证实了皮质多巴胺神经末梢的存在。这证实了先前关于皮质中多巴胺水平高的生化报告。组织化学显示，其分布具有区域性，且局限于边缘皮质。

相似文献

1
Dopamine nerve terminals in the rat limbic cortex: aspects of the dopamine hypothesis of schizophrenia.大鼠边缘叶皮质中的多巴胺神经末梢：精神分裂症多巴胺假说的相关方面
Science. 1974 Apr 12;184(4133):177-9. doi: 10.1126/science.184.4133.177.
2
Pharmaco-histochemical evidence of the existence of dopamine nerve terminals in the limbic cortex.边缘皮质中多巴胺神经末梢存在的药理组织化学证据。
Eur J Pharmacol. 1974 Jan;25(1):108-12. doi: 10.1016/0014-2999(74)90101-0.
3
Reversal by L-DOPA of the suppression of locomotor activity induced by inhibition of tyrosine-hydroxylase and DA-beta-hydroxylase in mice.左旋多巴对小鼠中因酪氨酸羟化酶和多巴胺β-羟化酶抑制所诱导的运动活动抑制的逆转作用。
Brain Res. 1974 Mar 29;69(1):57-65. doi: 10.1016/0006-8993(74)90370-9.
4
Heterogeneity of striatal and limbic dopamine innervation: highly fluorescent islands in developing and adult rats.纹状体和边缘系统多巴胺神经支配的异质性：发育中和成年大鼠中的高荧光岛
Brain Res. 1972 Sep 15;44(1):283-8. doi: 10.1016/0006-8993(72)90385-x.
5
Comparison of centrally mediated hypotensive action of methyldopa and DOPA in cats.甲基多巴与多巴对猫中枢介导的降压作用比较
Arch Int Pharmacodyn Ther. 1973 Sep;205(1):103-13.
6
Does dopamine play a role in schizophrenia?多巴胺在精神分裂症中起作用吗？
Psychol Med. 1977 Nov;7(4):583-97. doi: 10.1017/s003329170000622x.
7
Evidence for a centrally mediated hypotensive effect of L-dopa in the rat.左旋多巴对大鼠具有中枢介导的降压作用的证据。
J Pharm Pharmacol. 1970 Mar;22(3):241-3. doi: 10.1111/j.2042-7158.1970.tb08510.x.
8
Tyrosine hydroxylase and dopamine-beta-hydroxylase: distribution in discrete areas of the rat limbic system.酪氨酸羟化酶和多巴胺-β-羟化酶：在大鼠边缘系统离散区域的分布
Brain Res. 1976 Apr 9;105(3):517-24. doi: 10.1016/0006-8993(76)90597-7.
9
Immunohistochemical localization of dopamine- -hydroxylase in the peripheral and central nervous system.多巴胺-β-羟化酶在周围和中枢神经系统中的免疫组织化学定位。
Res Commun Chem Pathol Pharmacol. 1970 Sep;1(5):627-36.
10
Effect of desipramine on rat cortex slices incubated with 3H-dopamine.去甲丙咪嗪对用3H-多巴胺孵育的大鼠皮层切片的作用。
Psychopharmacologia. 1974;37(4):341-9. doi: 10.1007/BF00428920.

引用本文的文献

1
Circuit dynamics of the olfactory pathway during olfactory learning.嗅觉通路在嗅觉学习过程中的电路动力学。
Front Neural Circuits. 2024 Jul 5;18:1437575. doi: 10.3389/fncir.2024.1437575. eCollection 2024.
2
Brain-wide genetic mapping identifies the indusium griseum as a prenatal target of pharmacologically unrelated psychostimulants.全脑基因图谱定位发现灰结节为药理学上无关的精神兴奋剂的产前靶点。
Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25958-25967. doi: 10.1073/pnas.1904006116. Epub 2019 Dec 3.
3
How may the basal ganglia contribute to auditory categorization and speech perception?
基底神经节如何有助于听觉分类和言语感知？
Front Neurosci. 2014 Aug 1;8:230. doi: 10.3389/fnins.2014.00230. eCollection 2014.
4
The role of dopamine in schizophrenia from a neurobiological and evolutionary perspective: old fashioned, but still in vogue.从神经生物学和进化角度看多巴胺在精神分裂症中的作用：虽老套，但仍流行。
Front Psychiatry. 2014 May 19;5:47. doi: 10.3389/fpsyt.2014.00047. eCollection 2014.
5
Dopamine neurons in the ventral tegmental area: an autopsy case of disorganized type of schizophrenia.腹侧被盖区的多巴胺能神经元：一例紊乱型精神分裂症的尸检病例
Case Rep Neurol Med. 2011;2011:381059. doi: 10.1155/2011/381059. Epub 2011 Sep 22.
6
Bromocriptine and dopamine receptor stimulation.溴隐亭和多巴胺受体刺激。
Br J Clin Pharmacol. 1976 Dec;3(6):977-82. doi: 10.1111/j.1365-2125.1976.tb00346.x.
7
Projections from the rat pedunculopontine and laterodorsal tegmental nuclei to the anterior thalamus and ventral tegmental area arise from largely separate populations of neurons.大鼠脚桥核和外侧被盖核向前丘脑和腹侧被盖区的投射来自于神经元的两个不同群体。
Brain Struct Funct. 2011 Nov;216(4):331-45. doi: 10.1007/s00429-011-0320-2. Epub 2011 May 10.
8
Neurotransmitters and prefrontal cortex-limbic system interactions: implications for plasticity and psychiatric disorders.神经递质与前额叶皮质-边缘系统相互作用：对可塑性及精神疾病的影响
J Neural Transm (Vienna). 2009 Aug;116(8):941-52. doi: 10.1007/s00702-009-0243-8. Epub 2009 May 28.
9
Stimulation of D2 receptors in the prefrontal cortex reduces PCP-induced hyperactivity, acetylcholine release and dopamine metabolism in the nucleus accumbens.刺激前额叶皮质中的D2受体可降低苯环己哌啶诱导的活动亢进、乙酰胆碱释放及伏隔核中的多巴胺代谢。
J Neural Transm (Vienna). 2007 Feb;114(2):185-93. doi: 10.1007/s00702-006-0533-3. Epub 2006 Aug 8.
10
The neural consequences of repeated cocaine exposure revealed by functional MRI in awake rats.清醒大鼠功能性磁共振成像揭示的反复接触可卡因的神经后果
Neuropsychopharmacology. 2005 May;30(5):936-43. doi: 10.1038/sj.npp.1300653.