帕金森病左旋多巴治疗中的“开-关”现象。临床与药理学相关性及肌肉注射维生素B6的作用 - Suppr

"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.

作者信息

Fahn S

出版信息

Neurology. 1974 May;24(5):431-41. doi: 10.1212/wnl.24.5.431.

DOI:10.1212/wnl.24.5.431

PMID:4857104

Abstract

摘要

相似文献

"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.

Neurology. 1974 May;24(5):431-41. doi: 10.1212/wnl.24.5.431.

Levodopa, carbidopa, and pyridoxine in Parkinson disease. Metabolic interactions.

Arch Neurol. 1974 Jun;30(6):444-7. doi: 10.1001/archneur.1974.00490360020005.

Metabolic interactions of pyridoxine, levodopa, and carbidopa in Parkinson's disease.

Trans Am Neurol Assoc. 1973;98:241-5.

L-Dopa, B 6 , and alpha-methyldopa hydrazine.

Confin Neurol. 1973;35(3):186-92.

MK 486 and levodopa in treatment of Parkinsonism.

Dis Nerv Syst. 1973 Apr-May;34(4):167-71.

Ro 4-4602 and levodopa in the treatment of Parkinsonism.

Neurology. 1974 May;24(5):482-6. doi: 10.1212/wnl.24.5.482.

Parkinsonism-dementia of Guam: treatment with levodopa and L-alpha-methyldopahydrazine.

Neurology. 1974 Mar;24(3):263-5. doi: 10.1212/wnl.24.3.263.

Levodopa in Parkinsonism: potentiation of central effects with a peripheral inhibitor.

N Engl J Med. 1972 Jan 6;286(1):8-14. doi: 10.1056/NEJM197201062860102.

Levodopa combined with MK 486 (L-alpha methyldopahydrazine)--a peripheral decarboxylase inhibitor in Parkinson's disease.

Med J Aust. 1974 Mar 23;1(12):429-32.

Plasma concentration of levodopa in Parkinsonism before and after inhibition of peripheral decarboxylase.

J Neurol Sci. 1972 Sep;17(1):45-51. doi: 10.1016/0022-510x(72)90021-4.

引用本文的文献

Implication of regional selectivity of dopamine deficits in impaired suppressing of involuntary movements in Parkinson's disease.

Neurosci Biobehav Rev. 2024 Jul;162:105719. doi: 10.1016/j.neubiorev.2024.105719. Epub 2024 May 17.

Metabolite profiling of foslevodopa/foscarbidopa in plasma of healthy human participants by LC-HRMS indicates no major differences compared to administration of levodopa/carbidopa intestinal gel.

Pharmacol Res Perspect. 2024 Apr;12(2):e1190. doi: 10.1002/prp2.1190.

Role of dopamine agonists in Parkinson's disease therapy.

J Neural Transm (Vienna). 2023 Jun;130(6):863-873. doi: 10.1007/s00702-023-02647-0. Epub 2023 May 11.

Why do 'OFF' periods still occur during continuous drug delivery in Parkinson's disease?

Transl Neurodegener. 2022 Oct 13;11(1):43. doi: 10.1186/s40035-022-00317-x.

Parkinson's disease, dopaminergic drugs and the plant world.

Front Pharmacol. 2022 Sep 5;13:970714. doi: 10.3389/fphar.2022.970714. eCollection 2022.

How I treat Parkinson's disease.

Arq Neuropsiquiatr. 2022 May;80(5 Suppl 1):94-104. doi: 10.1590/0004-282X-ANP-2022-S126.

How to Optimize the Effectiveness and Safety of Parkinson's Disease Therapy? - A Systematic Review of Drugs Interactions with Food and Dietary Supplements.

Curr Neuropharmacol. 2022;20(7):1427-1447. doi: 10.2174/1570159X19666211116142806.

in Parkinson disease: A double-blind, randomized, controlled, crossover study.

Neurology. 2017 Aug 1;89(5):432-438. doi: 10.1212/WNL.0000000000004175. Epub 2017 Jul 5.

Development of new levodopa treatment strategies in Parkinson's disease-from bedside to bench to bedside.

Ups J Med Sci. 2017 Jun;122(2):71-77. doi: 10.1080/03009734.2017.1285374. Epub 2017 Mar 3.

Gene-based therapy of Parkinson's Disease: Translation from animal model to human clinical trial employing convection enhanced delivery.

Ann Neurosci. 2012 Jul;19(3):133-46. doi: 10.5214/ans.0972.7531.190310.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.

作者信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献