Taylor T K, Senekjian H O, Knight T F, Györkey F, Weinman E J
Arch Intern Med. 1979 Oct;139(10):1183-5.
Renal failure in patients with pulmonary or extrapulmonary sarcoidosis has been attributed to interstitial disease. Reports of cases of primary glomerular abnormality with renal failure in patients with sarcoidosis are rare. We describe a patient with pulmonary sarcoidosis and renal failure due to membranous nephropathy with epithelial crescents. A review of primary glomerular involvement in patients with sarcoidosis and the association of immune complexes in the pathogenesis of the two diseases is discussed.
肺部或肺外结节病患者的肾衰竭被认为与间质性疾病有关。结节病患者出现原发性肾小球异常伴肾衰竭的病例报告很少。我们描述了一名患有肺部结节病且因伴有上皮性新月体的膜性肾病而导致肾衰竭的患者。本文还讨论了结节病患者原发性肾小球受累情况以及两种疾病发病机制中免疫复合物的关联。